CHEGAEV, Konstantin
 Distribuzione geografica
Continente #
NA - Nord America 5.002
EU - Europa 2.811
AS - Asia 1.423
SA - Sud America 45
AF - Africa 25
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 6
Totale 9.332
Nazione #
US - Stati Uniti d'America 4.926
CN - Cina 875
IT - Italia 755
IE - Irlanda 424
SE - Svezia 297
DE - Germania 284
FR - Francia 200
UA - Ucraina 171
FI - Finlandia 166
PL - Polonia 127
GB - Regno Unito 121
SG - Singapore 112
AT - Austria 108
KR - Corea 102
JP - Giappone 68
CA - Canada 67
IN - India 63
VN - Vietnam 60
RU - Federazione Russa 49
TW - Taiwan 43
BR - Brasile 29
ES - Italia 29
TR - Turchia 22
HK - Hong Kong 20
NL - Olanda 19
BE - Belgio 11
EG - Egitto 11
AU - Australia 10
NZ - Nuova Zelanda 10
MX - Messico 9
CH - Svizzera 8
GR - Grecia 8
JO - Giordania 8
SN - Senegal 7
EU - Europa 6
IR - Iran 6
MY - Malesia 6
TH - Thailandia 6
AE - Emirati Arabi Uniti 5
AR - Argentina 5
BG - Bulgaria 5
CL - Cile 5
DK - Danimarca 5
ID - Indonesia 5
PT - Portogallo 5
NO - Norvegia 4
RO - Romania 4
UZ - Uzbekistan 4
CY - Cipro 3
EC - Ecuador 3
HU - Ungheria 3
IQ - Iraq 3
MU - Mauritius 3
AF - Afghanistan, Repubblica islamica di 2
AM - Armenia 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
HR - Croazia 2
IL - Israele 2
NG - Nigeria 2
PK - Pakistan 2
QA - Qatar 2
SI - Slovenia 2
UY - Uruguay 2
CO - Colombia 1
LB - Libano 1
RS - Serbia 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 9.332
Città #
Ann Arbor 505
Fairfield 501
Chandler 466
Beijing 431
Dublin 419
Ashburn 354
Houston 251
Woodbridge 220
Torino 218
Wilmington 196
Seattle 173
Dearborn 160
Pisa 152
Cambridge 150
Villeurbanne 121
Jacksonville 120
Warsaw 118
Nyköping 115
Medford 107
Vienna 104
Princeton 93
Redwood City 84
Fremont 69
Singapore 62
Munich 38
Boston 36
Taipei 36
Shanghai 34
Guangzhou 33
Hangzhou 29
Dong Ket 28
Milan 27
Boardman 26
New York 26
San Diego 26
Turin 26
Helsinki 24
Toronto 24
Nanjing 23
Zhengzhou 22
Ottawa 21
Siena 21
Tokyo 21
Jinan 20
Washington 20
Verona 19
Norwalk 18
Wuhan 17
Kunming 16
Toledo 15
Shenyang 12
Brussels 11
Naples 11
Upper Marlboro 11
Xian 11
Changsha 10
Florence 10
Hefei 9
Nuremberg 9
Nürnberg 9
Phoenix 9
Rome 9
Chengdu 8
Falls Church 8
Hebei 8
Moscow 8
Nanchang 8
Pune 8
Silver Spring 8
Buffalo 7
Rivoli 7
Cairo 6
Changchun 6
Dallas 6
Farmington 6
Lachine 6
Nanning 6
Tianjin 6
Amman 5
Bari 5
Catania 5
Chioggia 5
Chongqing 5
Des Moines 5
Fort Lauderdale 5
Granada 5
Leinì 5
London 5
Philadelphia 5
San Jose 5
Tappahannock 5
Woodside 5
Ankara 4
Bangkok 4
Bologna 4
Buenos Aires 4
Central District 4
Fuzhou 4
Goianesia Do Para 4
Monmouth Junction 4
Totale 6.170
Nome #
H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance 400
Light-Regulated NO Release as a Novel Strategy To Overcome Doxorubicin Multidrug Resistance 282
Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts 275
New furoxan derivatives for the treatment of ocular hypertension 270
Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance. 262
NO-donor thiacarbocyanines as multifunctional agents for Alzheimer’s disease 255
Overcoming multidrug resistance by targeting mitochondria with NO-donating doxorubicins 251
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors 250
Doxorubicin-antioxidant multitarget drugs 248
Edaravone derivatives containing NO-donor functions 205
(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins 189
Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis 179
Phenylsulfonylfuroxans as Modulators of Multidrug-Resistance-Associated Protein-1 and P-Glycoprotein 172
Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis 168
Liposomal Nitrooxy-Doxorubicin: One Step over Caelyx in Drug-Resistant Human Cancer Cells 167
Solid lipid nanoparticles carrying lipophilic derivatives of doxorubicin: preparation, characterization, and in vitro cytotoxicity studies 165
New nitric oxide or hydrogen sulfide releasing aspirins 164
Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs 164
Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity 159
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants 156
Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents 155
Effects of Nitric Oxide Donor Antioxidants Containing the Phenol Vitamin E Substructure and a Furoxan Moiety on Ischemia/Riperfusion Injury 147
Direct introduction of cyano group on furoxan ring 135
gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension 134
NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties 131
Solid Lipid Nanoparticles Loaded with Antitumor Lipophilic Prodrugs Aimed to Glioblastoma Treatment: Preliminary Studies on Cultured Cells 127
A Nitric Oxide-Donor Furoxan Moiety Improves the Efficacy of Edaravone against Early Renal Dysfunction and Injury Evoked by Ischemia/Reperfusion 123
Amphiphilic NO-Donor Antioxidants 123
Synthesis and Biological Evaluation of N2-Substituted 2,4-Diamino-6-cyclohexylmethoxy-5-nitrosopyrimidines and Related 5-Cyano-NNO-azoxy Derivatives as Cyclin-Dependent Kinase 2 (CDK2) Inhibitors 121
NO-Donor Melatonin Derivatives: Synthesis And In Vitro Pharmacological Characterization 116
Novel Antioxidant Agents Deriving From Molecular Combination of Vitamin C and NO-donor moieties 114
Multitarget Drugs: Focus on the NO-donor hybrid drugs 114
Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity 114
Synthesis of Some Novel Organic Nitrates and Comparative in Vitro Study of Their Vasodilator Profile 109
Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors 108
New tetrahydroisoquinoline derivatives overcome pgp activity in brain-blood barrier and glioblastoma multiforme in vitro 103
NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties 102
Aceclofenac-galactose conjugate: design, synthesis, characterization and pharmacological and toxicological evaluations 101
Mitochondrial delivery of phenol substructure triggers mitochondrial depolarization and apoptosis of cancer cells 97
Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma 95
Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug 95
Leishmanicidal Activity of Novel Synthetic Furoxan and Benzofuroxan Derivatives 93
New NO- and H2S-releasing doxorubicins as targeted therapy against chemoresistance in castration-resistant prostate cancer: in vitro and in vivo evaluations 82
New tetrahydroisoquinoline-based P-glycoprotein modulators: Decoration of the biphenyl core gives selective ligands 82
Novel Organic Nitrate Esters 81
Evaluation of the targeting ability of folate containing liposomal nitrooxy-doxorubicin. 80
NO-Donor Furoxans Containing a Sulphonamide Moiety and Related Furazans as Potent Carbonic Anhydrase Inhibitors 78
Amphiphile NO-donor antioxidants as polivalent drugs 76
Nitrooxy-doxorubicin: A New Weapon Against Multidrug Resistance. 74
MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells 74
PREPARATION AND CHARACTERIZATION OF LIPOSOMES CONTAINING A NEW ANTHRACYCLINE DERIVATIVE 72
NITRIC OXIDE DONOR DOXORUBICINS: A USEFUL STRATEGY TO ADDRESS THE PROBLEM OF MDR IN CANCER THERAPY 71
Highly diastereoselective synthesis of 2-monosubstituted 1R,5S(1S,5R)-glycoluriles on the basis of S- and R-N-carbamoyl-alpha-amino acids 69
Multitarget Drugs: No-Donor Doxorubicins 68
Synthesis of new heterocyclic sulfamides 66
Novel amphiphilic nitric oxide releasing antioxidants: NMR spectroscopic study of their interaction with biomembrane models 65
NO-Donor Cyanines As Potential Anti-Alzheimer Drugs 64
Reactions of sulfonamides with 4,5-dihydroxyimidazolidin-2-ones 61
PHENYLSULFONYL FUROXANS AS MODULATORS OF MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN-1 AND P-GLYCOPROTEIN 59
INCAPSULATED NO-GEMCITABINE: GASEOUS SOLUTION FOR MDR PANCREATIC CANCER 58
Low concentrations of an nitric oxide-donor combined with a liposoluble antioxidant compound enhance protection against reperfusion injury in isolated rat hearts 57
Novel NO-donor Doxorubicins 57
MODIFIED DOXORUBICINS: "GASEOUS APPROACH" TO OVERCOME CARDIOTOXICITY AND MULTIDRUG RESISTANCE 57
Unsymmetrically Substituted Furoxans. Part 19. Methyl and Phenylfuroxansulfonic Acids and Related Sulfonamides 56
NOVEL SEMISYNTHETIC DOXORUBICINS WITH REDUCED CARDIOTOXICITY 54
NO donor - melatonins: a new class of potential antiatherosclerosis agents 53
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation 52
A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors 52
Vasodilating profile of a new series of analogues of GTN 51
New functional glycoluril derivatives 49
Preparation and characterization of liposomes containing a new anthracycline derivative. 49
Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers 48
The N-silylation reaction of 2,4,6-trialkyl-2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-diones 48
Multitarget drugs: NO-donor doxorubicins 47
Tolerance profile of new organic nitrates with antioxidant properties 46
Screening for potential hazard effects from a multitarget anthracycline on the cardiovascular system 46
Synthesis of 2-monofunctionalized 2,4,6,8-tetraazabicyclo[3.3.0]octane-3,7-diones 43
Nitric oxide release by an edavarone derivative containing NOdonor furoxan moiety contributes to the resolution of renal injury after ischemia/reperfusion in the rat 42
Nitric oxide donor-doxorubicins as mdr reversing agents 41
MITOCHONDRIAL-TARGETING NITROOXYDOXORUBICIN: EFFECTS ON P-GLYCOPROTEIN AND ASSESSMENT OF THEIR VASCULAR EFFECTS 40
IN VITRO CARDIOVASCULAR TOXICITY RISK ASSESSMENT OF NOVEL H2S-DONATING ANTHRACYCLINE 40
Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4′-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Selective Ligands of P-glycoprotein 38
Reactions of N-alkylglycolurils with electrophilic reagents 37
Planning, synthesis and anti-Mycobacterium tuberculosis activity of N-oxide derivatives 34
NO-donor aspirin derivatives 32
Screening for potential hazard effects from multitarget anthracyclines on vasculature 32
SCREENING FOR POTENTIAL HAZARD EFFECTS FROM MULTITARGET ANTHRACYCLINE ON THE CARDIOVASCULAR SYSTEM 31
Comparative Study of Different H2S Donors as Vasodilators and Attenuators of Superoxide-Induced Endothelial Damage 29
Synthesis, physical-chemical and pharmacological studies of new organic nitrates as novel potent vasodilatators 29
NO release regulated by doxorubicin as the green light-harvesting antenna 26
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation 24
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature 23
Multitarget antioxidant NO-donor organic nitrates: a novel ap-proach to overcome nitrates tolerance, an ex vivo study 22
Naked and Decorated Nanoparticles Containing H2S-Releasing Doxorubicin: Preparation, Characterization and Assessment of Their Antitumoral Efficiency on Various Resistant Tumor Cells 20
In vitro vascular toxicity assessment of NitDOX, a novel NO-releasing doxorubicin 15
New lipophilic organic nitrates: Candidates for chronic skin disease therapy 11
Use of Enzymatically Activated Carbon Monoxide Donors for Sensitizing Drug-Resistant Tumor Cells 8
Multitarget antioxidant NO-donor organic nitrates: a novel approach to overcome nitrates tolerance 7
Totale 9.664
Categoria #
all - tutte 25.346
article - articoli 0
book - libri 0
conference - conferenze 4.914
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.260


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.669 58 67 93 220 98 220 165 131 198 181 130 108
2020/20211.180 98 92 86 63 115 74 65 86 170 114 83 134
2021/20221.403 87 84 99 133 69 49 101 87 59 88 322 225
2022/20231.542 148 145 32 118 113 374 214 86 160 56 57 39
2023/2024904 84 131 56 35 71 168 42 42 13 85 67 110
2024/202510 10 0 0 0 0 0 0 0 0 0 0 0
Totale 9.664