GHIGO, Alessandra
 Distribuzione geografica
Continente #
NA - Nord America 6.195
EU - Europa 3.950
AS - Asia 2.048
SA - Sud America 80
AF - Africa 55
OC - Oceania 42
Continente sconosciuto - Info sul continente non disponibili 5
Totale 12.375
Nazione #
US - Stati Uniti d'America 6.110
DK - Danimarca 1.338
CN - Cina 1.190
IT - Italia 807
SG - Singapore 426
IE - Irlanda 350
DE - Germania 305
SE - Svezia 239
FR - Francia 179
FI - Finlandia 119
UA - Ucraina 119
JP - Giappone 96
GB - Regno Unito 87
AT - Austria 81
BE - Belgio 77
CA - Canada 75
KR - Corea 75
BR - Brasile 73
PT - Portogallo 64
PL - Polonia 61
IN - India 58
HK - Hong Kong 45
VN - Vietnam 45
CH - Svizzera 44
AU - Australia 41
TW - Taiwan 26
ID - Indonesia 23
IR - Iran 22
NL - Olanda 20
ES - Italia 17
SN - Senegal 15
RU - Federazione Russa 12
ET - Etiopia 10
NG - Nigeria 10
TH - Thailandia 9
NO - Norvegia 8
CZ - Repubblica Ceca 6
IL - Israele 6
MX - Messico 6
TR - Turchia 6
ZA - Sudafrica 6
EU - Europa 5
BD - Bangladesh 4
SI - Slovenia 4
AR - Argentina 3
EG - Egitto 3
GR - Grecia 3
HU - Ungheria 3
MO - Macao, regione amministrativa speciale della Cina 3
MY - Malesia 3
NP - Nepal 3
PK - Pakistan 3
BW - Botswana 2
BY - Bielorussia 2
BZ - Belize 2
MA - Marocco 2
MU - Mauritius 2
RO - Romania 2
UG - Uganda 2
UY - Uruguay 2
CO - Colombia 1
CR - Costa Rica 1
CY - Cipro 1
EC - Ecuador 1
GH - Ghana 1
GP - Guadalupe 1
IQ - Iraq 1
IS - Islanda 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MK - Macedonia 1
NE - Niger 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PS - Palestinian Territory 1
ZM - Zambia 1
Totale 12.375
Città #
Ann Arbor 1.594
Chandler 676
Santa Clara 484
Singapore 350
Dublin 349
Beijing 281
Ashburn 273
Torino 255
Houston 244
Shenyang 216
Wilmington 211
Fairfield 159
Nyköping 137
Dearborn 112
Turin 105
Columbus 100
Villeurbanne 93
Medford 86
Princeton 86
Vienna 79
Jacksonville 74
Guangzhou 71
Boston 70
Seattle 68
Munich 62
Redwood City 60
Hangzhou 54
Woodbridge 52
Milan 48
Warsaw 41
Helsinki 39
Cambridge 35
Pisa 32
Shanghai 31
Chennai 29
Fremont 29
Grafing 29
Montréal 29
Nanjing 29
Palaiseau 25
Asti 23
Brussels 23
Seoul 23
Fortaleza 22
Los Angeles 22
Buffalo 21
Tokyo 21
Dong Ket 20
Maasmechelen 20
Rome 20
Chengdu 19
Jakarta 19
Hong Kong 17
Verona 17
Boardman 16
Hebei 16
Wuhan 16
Baltimore 15
Falls Church 15
New York 14
San Diego 14
Taipei 14
Evanston 13
Pittsburgh 13
Atlanta 12
Castellana Grotte 12
Copenhagen 12
Hasselt 12
Brisbane 11
Campinas 11
Guiyang 11
Hefei 11
Kunming 11
Berlin 10
Chicago 10
Chongqing 10
Norwalk 10
Bornem 9
Falkenstein 9
Kyoto 9
Paris 9
Sydney 9
Toronto 9
Heidelberg 8
Hyderabad 8
Lappeenranta 8
London 8
Ottawa 8
Phoenix 8
Shenzhen 8
Trieste 8
Washington 8
Xian 8
Zhengzhou 8
Abuja 7
Bonn 7
Central 7
Des Moines 7
Jinan 7
Madrid 7
Totale 7.557
Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 676
Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth 647
Hemopexin Therapy Improves Cardiovascular Function by Preventing Heme-Induced Endothelial Toxicity in Mouse Models of Hemolytic Diseases 526
Hemopexin counteracts systolic dysfunction induced by heme-driven oxidative stress 504
Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting 337
Distinct Effects of Leukocyte and Cardiac Phosphoinositide 3-Kinase {gamma} Activity in Pressure Overload-Induced Cardiac Failure 297
Pulmonary-derived phosphoinositide 3-kinase gamma (PI3Kγ) contributes to ventilator-induced lung injury and edema. 253
Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation 250
Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases. 248
Integrating Cardiac PIP(3) and cAMP Signaling through a PKA Anchoring Function of p110γ. 243
Myocyte signalling in leucocyte recruitment to the heart. 232
Crossroads of PI3K and Rac pathways 230
Identification of the macromolecular complex responsible for PI3Kgamma-dependent regulation of cAMP levels. 229
Anchoring proteins as regulators of signaling pathways. 227
Therapeutic applications of PI3K inhibitors in cardiovascular diseases. 225
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling 222
PI3K in cancer-stroma interactions: bad in seed and ugly in soil. 220
Ablation of Calcineurin Aβ Reveals Hyperlipidemia and Signaling Cross-talks with Phosphodiesterases. 216
Dietary ω-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease 216
Specific PI3K Isoform Modulation in Heart Failure: Lessons from Transgenic Mice. 214
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits 211
PI3K inhibition in inflammation:Toward tailored therapies for specific diseases 207
Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity 206
NADPH Oxidases in Heart Failure: Poachers or Gamekeepers? 206
Taming the PI3K team to hold inflammation and cancer at bay 205
Phosphoinositide 3-kinases in health and disease. 200
Hyper-activation of the Rho-GTPase Rac1 via disruption of ArhGAP15 results in reduced architectural and functional complexity 198
Elastin degradation and ensuing inflammation as emerging keys to atherosclerosis. 191
Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics 190
Phosphoinositides and cardiovascular diseases. 189
null 186
Isoform Selective Phosphoinositide 3-Kinase gamma and delta Inhibitors and Their Therapeutic Potential 182
Metabolic Aspects of Anthracycline Cardiotoxicity 174
Antineoplastic drug-induced cardiotoxicity: A redox perspective 159
Data demonstrating the anti-oxidant role of hemopexin in the heart 153
Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits 153
Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function 150
Therapeutic Targeting of PDEs and PI3K in Heart Failure with Preserved Ejection Fraction (HFpEF) 134
A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases 129
Dysfunctional inflammation in cystic fibrosis airways: From mechanisms to novel therapeutic approaches 97
The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity 87
Pi3k signaling in chronic obstructive pulmonary disease: Mechanisms, targets, and therapy 85
Liver-Specific siRNA-Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis 85
Rac signal adaptation controls neutrophil mobilization from the bone marrow 81
New signal transduction paradigms in anthracycline-induced cardiotoxicity 79
Tregs restrain dendritic cell autophagy to ameliorate autoimmunity 78
Data demonstrating the role of peroxiredoxin 2 as important anti-oxidant system in lung homeostasis 77
Phosphoinositide 3-kinase: friend and foe in cardiovascular disease 75
PI3K and Calcium Signaling in Cardiovascular Disease 75
Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs 75
Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function 74
Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure 73
Potential therapeutic applications of AKAP disrupting peptides 73
PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation 71
PI3Ks in Diabetic Cardiomyopathy 70
Cancer Risk in the Heart Failure Population: Epidemiology, Mechanisms, and Clinical Implications 70
Mechanisms underlying the cross-talk between heart and cancer 68
Signaling pathways underlying anthracycline cardiotoxicity 66
Autophagy and cancer therapy cardiotoxicity: From molecular mechanisms to therapeutic opportunities 66
Peroxiredoxin-2 plays a pivotal role as multimodal cytoprotector in the early phase of pulmonary hypertension 65
Preventing and Treating Anthracycline Cardiotoxicity: New Insights 65
A novel protective role for activating transcription factor 3 in the cardiac response to metabolic stress 64
Cardiac dysfunction in cancer patients: Beyond direct cardiomyocyte damage of anticancer drugs: Novel cardio-oncology insights from the joint 2019 meeting of the ESC working groups of myocardial function and cellular biology of the heart 62
Inhaled Biologicals for the Treatment of Cystic Fibrosis 61
Therapeutic peptides for the treatment of cystic fibrosis: Challenges and perspectives 61
The human fetal and adult stem cell secretome can exert cardioprotective paracrine effects against cardiotoxicity and oxidative stress from cancer treatment 58
Cell-specific roles of p110β in myocardial ischemia 56
The Interplay Between Autophagy and Senescence in Anthracycline Cardiotoxicity 56
Mechanisms of Anthracycline-Induced Cardiotoxicity: Is Mitochondrial Dysfunction the Answer? 54
An integrated approach to cardioprotection in lymphomas 53
cAMP/PKA signaling compartmentalization in cardiomyocytes: Lessons from FRET-based biosensors 52
New avenues in cardio-oncology 51
Role of Protein Kinase A-Mediated Phosphorylation in CFTR Channel Activity Regulation 49
Cell signaling and regulation of CFTR expression in cystic fibrosis cells in the era of high efficiency modulator therapy 47
Response by Vandecasteele et al to Letter Regarding Article, âCardiac Overexpression of PDE4B Blunts Î-Adrenergic Response and Maladaptive Remodeling in Heart Failureâ 47
Oxidative stress in anticancer therapies-related cardiac dysfunction 47
Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia 46
'Circulating' RNA-based therapies in Cardio-Oncology 45
Leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure. 42
Duality of Nrf2 in iron-overload cardiomyopathy 41
Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive. 40
A non-catalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage 40
Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development 37
Roles of phosphatidyl inositol 3 kinase gamma (PI3Kγ) in respiratory diseases 34
Preclinical Models of Cancer Therapy-Associated Cardiovascular Toxicity: A Scientific Statement From the American Heart Association 33
Neurotoxic Effect of Doxorubicin Treatment on Cardiac Sympathetic Neurons 32
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide 32
It Takes Two to Tango! Protein–Protein Interactions behind cAMP-Mediated CFTR Regulation 29
Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice 26
In Humanized Sickle Cell Mice, Imatinib Protects Against Sickle Cell-Related Injury 25
Illuminating cAMP Dynamics at Ryanodine Receptors in Arrhythmias 25
MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation 24
Pi3k as mediator of apoptosis and contractile dysfunction in tgfβ1-stimulated cardiomyocytes 24
Young@Heart: empowering the next generation of cardiovascular researchers 23
Emerging Roles of Phospholipase C Beta Isozymes as Potential Biomarkers in Cardiac Disorders 22
Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation 22
An intrinsic mechanism of metabolic tuning promotes cardiac resilience to stress 19
p53 at the Intersection of Cardiac Fibroblast Proliferation and Activation: Answers and Questions 17
Extracellular vesicles derived from human livers stem cells counteract chronic kidney disease development and cardiac dysfunction in remnant kidney murine model: the possible involvement of proteases 16
Editorial: Cardio-oncology and reverse cardio-oncology: the manifold interconnections between heart failure and cancer 13
Totale 12.815
Categoria #
all - tutte 34.222
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.222


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.725 0 0 0 0 0 306 273 209 217 242 232 246
2020/2021949 73 40 30 23 75 43 116 25 139 81 58 246
2021/20222.361 236 231 197 243 192 191 176 172 143 103 240 237
2022/20232.161 184 183 75 203 176 474 145 135 252 69 123 142
2023/20241.265 157 170 126 86 94 94 87 92 26 135 69 129
2024/20251.837 78 408 107 231 723 290 0 0 0 0 0 0
Totale 12.827